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Specification
| Full name | CFTR rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome. |
| Swissprot No | P13569 |
| Gene Accession | NP_000483 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or CFTR antigen-treated (Neutralization experiment) using P106057(CFTR Antibody) at dilution 1/50 |
| WB Positive control | P106057-WB-1-P |
| WB Recommended dilution | 168 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human colorectal cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P106057-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or CFTR antigen-treated (Neutralization experiment) using P106057(CFTR Antibody) at dilution 1/50
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Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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