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Sku: P102849-50 μl
Categories: Primary Antibodies

Specification

Full name CERS4 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis.
Swissprot No Q9HA82
Gene Accession NP_078828
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or CERS4 antigen-treated (Neutralization experiment) using P102849(CERS4 Antibody) at dilution 1/35
WB Positive control P102849-WB-1-P
WB Recommended dilution 46 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human ovarian cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P102849-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue or CERS4 antigen-treated (Neutralization experiment) using P102849(CERS4 Antibody) at dilution 1/35

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