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Full name | CERS4 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they are all involved in sphingolipid synthesis. LASS4 is a 394 amino acid endoplasmic reticulum, multi-pass membrane protein. LASS4 increases the levels of long ceramides such as C22:0- and C24:0-ceramides. In cells deficient for CLN9, as observed in neuronal ceroid lipofuscinosis (NCL) or Batten disease, LASS4 can increase ceramide levels and partially correct growth and apoptosis. |
Swissprot No | Q9HA82 |
Gene Accession | NP_078828 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or CERS4 antigen-treated (Neutralization experiment) using P102849(CERS4 Antibody) at dilution 1/35 |
WB Positive control | P102849-WB-1-P |
WB Recommended dilution | 46 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human ovarian cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P102849-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue or CERS4 antigen-treated (Neutralization experiment) using P102849(CERS4 Antibody) at dilution 1/35
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