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Full name | CDKN1B rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). |
Swissprot No | P46527 |
Gene Accession | BC001971 |
WB Predicted band size | |
WB Positive control | P114805-WB-1-P |
WB Recommended dilution | 22 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm and Nucleus |
IHC positive control | Positive control: Human prostate cancer |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P114805-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or CDKN1B antigen-treated (Neutralization experiment) using P114805(CDKN1B Antibody) at dilution 1/50
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