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Full name | CDH3 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a gene cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene are associated with hypotrichosis with juvenile macular dystrophy and ectodermal dysplasia, ectrodactyly, and macular dystrophy syndrome (EEMS). |
Swissprot No | P22223 |
Gene Accession | BC014462 |
WB Predicted band size | |
WB Positive control | P108079-WB-1-P |
WB Recommended dilution | 91 kDa |
IHC predicted cell location | Predicted cell location: Cell membrane |
IHC positive control | Positive control: Human cervical cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P108079-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or CDH3 antigen-treated (Neutralization experiment) using P108079(CDH3 Antibody) at dilution 1/90
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