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Full name | CD59 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. |
Swissprot No | P13987 |
Gene Accession | NP_000602 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or CD59 antigen-treated (Neutralization experiment) using P102673(CD59 Antibody) at dilution 1/50 |
WB Positive control | P102673-WB-1-P |
WB Recommended dilution | 14 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human thyroid cancer |
IHC Recommed dilution | Recommended dilution: 100-300 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P102673-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or CD59 antigen-treated (Neutralization experiment) using P102673(CD59 Antibody) at dilution 1/50
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