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Full name | CBX3 mouse monoclnal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | mouse monoclonal |
Applications | WB, IHC |
Host | Mouse |
Clone type | mouse monoclonal |
Target Background | At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene. |
Swissprot No | Q13185 |
Gene Accession | |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue using P114225(CBX3 Antibody) at dilution 1/150 |
WB Positive control | P114225-WB-1-P |
WB Recommended dilution | 21 kDa |
IHC predicted cell location | Predicted cell location: Nucleus |
IHC positive control | Positive control: Human colorectal cancer and Human gastric cancer |
IHC Recommed dilution | Recommended dilution: 100-500 |
Ascitic fluid with 0.05% sodium azide and 40% glycerol
P114225-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human colorectal cancer and Human gastric cancer tissue using P114225(CBX3 Antibody) at dilution 1/150
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