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Sku: P102610-50 μl
Categories: Primary Antibodies

Specification

Full name CAV1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.
Swissprot No Q03135
Gene Accession NP_001744
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or CAV1 antigen-treated (Neutralization experiment) using P102610(CAV1 Antibody) at dilution 1/40
WB Positive control P102610-WB-1-P
WB Recommended dilution 20 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human esophagus cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P102610-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or CAV1 antigen-treated (Neutralization experiment) using P102610(CAV1 Antibody) at dilution 1/40

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