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Full name | CAV1 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1. |
Swissprot No | Q03135 |
Gene Accession | NP_001744 |
WB Predicted band size | 20 kDa |
WB Positive control | |
WB Recommended dilution | 1000-5000 |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human esophagus cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P102610-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or CAV1 antigen-treated (Neutralization experiment) using P102610(CAV1 Antibody) at dilution 1/40
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