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Full name | CASP6 rabbit monoclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit monoclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit monoclonal |
Target Background | This gene encodes a member of the cysteine-aspartic acid protease (caspase) family of enzymes. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Oct 2015] |
Swissprot No | P55212 |
Gene Accession | 839 |
WB Predicted band size | 33 kDa |
WB Positive control | |
WB Recommended dilution | 500-2000 |
IHC predicted cell location | Predicted cell location: Cytoplasm and Nucleus |
IHC positive control | Positive control: Human colon cancer |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.
P290209-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P290209(CASP6 Antibody) at dilution 1/50
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