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Full name | CASP3 (active) rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. |
Swissprot No | P42574 |
Gene Accession | NP_116786 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or CASP3 (active) antigen-treated (Neutralization experiment) using P109536(CASP3 (active) Antibody) at dilution 1/50 |
WB Positive control | P109536-WB-1-P |
WB Recommended dilution | 17 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human colorectal cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P109536-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or CASP3 (active) antigen-treated (Neutralization experiment) using P109536(CASP3 (active) Antibody) at dilution 1/50
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