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Sku: P109536-50 μl

Specification

Full name CASP3 (active) rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The protein encoded by this gene is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease.
Swissprot No P42574
Gene Accession NP_116786
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or CASP3 (active) antigen-treated (Neutralization experiment) using P109536(CASP3 (active) Antibody) at dilution 1/50
WB Positive control P109536-WB-1-P
WB Recommended dilution 17 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human colorectal cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P109536-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or CASP3 (active) antigen-treated (Neutralization experiment) using P109536(CASP3 (active) Antibody) at dilution 1/50

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