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Full name | CAPN6 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain, and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. |
Swissprot No | Q9Y6Q1 |
Gene Accession | BC000730 |
WB Predicted band size | |
WB Positive control | P104583-WB-1-P |
WB Recommended dilution | 75 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P104583-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or CAPN6 antigen-treated (Neutralization experiment) using P104583(CAPN6 Antibody) at dilution 1/70
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