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Specification
| Full name | CAB39 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK). |
| Swissprot No | Q9Y376 |
| Gene Accession | NP_057373 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or CAB39 antigen-treated (Neutralization experiment) using P102887(CAB39 Antibody) at dilution 1/50 |
| WB Positive control | P102887-WB-1-P |
| WB Recommended dilution | 40 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm and Nucleus |
| IHC positive control | Positive control: Human cervical cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P102887-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or CAB39 antigen-treated (Neutralization experiment) using P102887(CAB39 Antibody) at dilution 1/50
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We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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