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Full name | BRI3BP rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells. |
Swissprot No | Q8WY22 |
Gene Accession | NP_542193 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or BRI3BP antigen-treated (Neutralization experiment) using P103211(BRI3BP Antibody) at dilution 1/35 |
WB Positive control | P103211-WB-1-P |
WB Recommended dilution | 28 kDa |
IHC predicted cell location | Predicted cell location: Cell membrane |
IHC positive control | Positive control: Human cervical cancer |
IHC Recommed dilution | Recommended dilution: 30-150 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P103211-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or BRI3BP antigen-treated (Neutralization experiment) using P103211(BRI3BP Antibody) at dilution 1/35
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