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Sku: P103211-50 μl

Specification

Full name BRI3BP rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background BRI3BP (BRI3 binding protein), also known as BNAS1, HCCR-1, I3-binding protein or cervical cancer 1 proto-oncogene-binding protein KG19, is a 251 amino acid multi-pass membrane protein. Though widely expressed, BRI3BP is found at highest levels in brain, kidney and liver where it localizes to the endoplasmic reticulum (ER) and is involved in ER structural dynamics and mitochondrial viability. Possessing pro-apoptotic properties and the ability to potentiate drug-induced apoptosis, BRI3BP overexpression has been shown to enhance caspase-3 and mitochondrial cytochrome c release in etoposide-treated human embryonic kidney 293T cells.
Swissprot No Q8WY22
Gene Accession NP_542193
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or BRI3BP antigen-treated (Neutralization experiment) using P103211(BRI3BP Antibody) at dilution 1/35
WB Positive control P103211-WB-1-P
WB Recommended dilution 28 kDa
IHC predicted cell location Predicted cell location: Cell membrane
IHC positive control Positive control: Human cervical cancer
IHC Recommed dilution Recommended dilution: 30-150

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P103211-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or BRI3BP antigen-treated (Neutralization experiment) using P103211(BRI3BP Antibody) at dilution 1/35

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