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Full name | BLNK rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. |
Swissprot No | Q8WV28 |
Gene Accession | NP_001107566 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue or BLNK antigen-treated (Neutralization experiment) using P102643(BLNK Antibody) at dilution 1/50 |
WB Positive control | P102643-WB-1-P |
WB Recommended dilution | 50 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human lung cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P102643-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue or BLNK antigen-treated (Neutralization experiment) using P102643(BLNK Antibody) at dilution 1/50
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