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Full name | BCL2L11 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. |
Swissprot No | O43521 |
Gene Accession | NP_006529 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or BCL2L11 antigen-treated (Neutralization experiment) using P107183(BCL2L11 Antibody) at dilution 1/30 |
WB Positive control | P107183-WB-1-P |
WB Recommended dilution | 22 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human ovarian cancer |
IHC Recommed dilution | Recommended dilution: 20-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P107183-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue or BCL2L11 antigen-treated (Neutralization experiment) using P107183(BCL2L11 Antibody) at dilution 1/30
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