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Sku: P107183-50 μl
Categories: Primary Antibodies

Specification

Full name BCL2L11 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified.
Swissprot No O43521
Gene Accession NP_006529
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or BCL2L11 antigen-treated (Neutralization experiment) using P107183(BCL2L11 Antibody) at dilution 1/30
WB Positive control P107183-WB-1-P
WB Recommended dilution 22 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human ovarian cancer
IHC Recommed dilution Recommended dilution: 20-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P107183-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue or BCL2L11 antigen-treated (Neutralization experiment) using P107183(BCL2L11 Antibody) at dilution 1/30

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