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Specification
| Full name | BCAS2 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | BCAS2 (breast carcinoma amplified sequence 2), also designated DAM1 (DNA amplified in mammary carcinoma 1 protein) or spliceosome-associated SPF 27, is a ubiquitously expressed nuclear protein that was originally identified as being overexpressed in various breast cancer cell lines. BCAS2 is now known to be a component of the spliceosome, participating in the removal of introns from mRNA precursors. BCAS2 specifically interacts (in a ligand-independent manner) with TR∫ (thyroid hormone receptor beta), ERå (estrogen receptor alpha), ER∫, PR (progesterone receptor), and PPAR© (Peroxisome proliferator-activated receptor gamma). BCAS2 functions as an ER coactivator and is capable of enhancing ER-mediated transcription. This suggests that BCAS2 is involved in the development of breast cancer. |
| Swissprot No | O75934 |
| Gene Accession | BC005285 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue or BCAS2 antigen-treated (Neutralization experiment) using P100665(BCAS2 Antibody) at dilution 1/50 |
| WB Positive control | P100665-WB-1-P |
| WB Recommended dilution | 26 kDa |
| IHC predicted cell location | Predicted cell location: Nucleus |
| IHC positive control | Positive control: Human colon cancer |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P100665-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue or BCAS2 antigen-treated (Neutralization experiment) using P100665(BCAS2 Antibody) at dilution 1/50
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Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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