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Sku: P290125-50 μl
Categories: Primary Antibodies

Specification

Full name ATP1B1 rabbit monoclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit monoclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit monoclonal
Target Background The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 1 subunit. Alternatively spliced transcript variants encoding different isoforms have been described, but their biological validity is not known. [provided by RefSeq, Mar 2010]
Swissprot No P05026
Gene Accession 481
WB Predicted band size
WB Positive control P290125-WB-1-P
WB Recommended dilution 35 kDa
IHC predicted cell location Predicted cell location: Cell membrane
IHC positive control Positive control: Human colon cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

WB PIC Description

P290125-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P290125(ATP1B1 Antibody) at dilution 1/50

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