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Specification
| Full name | AKT1 mouse monoclnal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | mouse monoclonal |
| Applications | WB, IHC |
| Host | Mouse |
| Clone type | mouse monoclonal |
| Target Background | The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. |
| Swissprot No | P31749 |
| Gene Accession | |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human colorectal cancer and Human esophagus cancer tissue using P113844(AKT1 Antibody) at dilution 1/150 |
| WB Positive control | P113844-WB-1-P |
| WB Recommended dilution | 56 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human lung cancer and Human liver cancer |
| IHC Recommed dilution | Recommended dilution: 100-500 |
Storage
Ascitic fluid with 0.05% sodium azide and 40% glycerol
WB PIC Description
P113844-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human lung cancer and Human liver cancer tissue using P113844(AKT1 Antibody) at dilution 1/150
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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