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Specification
| Full name | ACTL6B rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants. |
| Swissprot No | O94805 |
| Gene Accession | BC020944 |
| WB Predicted band size | |
| WB Positive control | P111658-WB-1-P |
| WB Recommended dilution | 47 kDa |
| IHC predicted cell location | Predicted cell location: Nucleus |
| IHC positive control | Positive control: Human esophagus cancer |
| IHC Recommed dilution | Recommended dilution: 50-300 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P111658-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or ACTL6B antigen-treated (Neutralization experiment) using P111658(ACTL6B Antibody) at dilution 1/55
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