Human TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), GA733-1, gp50 and T16, is a type I cell surface glycoprotein that is highly expressed on human carcinomas. The...
Bcakground Granulocyte Colony Stimulating Factor(G-CSF)is a pleiotropic cytokine best known for its specific effects on the proliferation, differentiation, and activation of hematopoietic cells of the neutrophilic granulocyte lineage. It is...
Bcakground Granulocyte Macrophage Growth Factor(GM-CSF) is one of an array of cytokines with pivotal roles in embryo implantation and subsequent development. In response to cytokine or inflammatory stimuli, GM-CSF is...
The dickkopf family of proteins are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling....
Bcakground Insulin-like Growth Factor II (IGF-II) is a potent mitogenic growth factor. However, unlike IGF-I which has important postnatal roles, the growth -promoting function of IGF-II is limited to embryonic...
Annexin A5 (or annexin V) is a cellular protein in the annexin group. In flow cytometry, annexin V is commonly used to detect apoptotic cells by its ability to bind...
Bcakground Interleukin-17A(IL-17A) , also known as CTLA-8, is a 15-20 kDa glycosylated cytokine that plays an important role in anti-microbial and chronic inflammation. The six IL-17 cytokines (IL-17A-F) are encoded...
Bcakground Interon-alpha (IFN-alpha),also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I...