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$336.00
Sku: Y12301-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by April 28, 2026
Description
VEGF121 is a soluble isoform of VEGF-A that lacks heparin-binding domains. It signals mainly through VEGFR-2 to promote endothelial cell proliferation and migration. VEGF121 is commonly used in vitro to support angiogenesis models and vascularization in organoid and tissue engineering systems.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y12301 |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | Measured in a cell proliferation assay using HUVEC human umbilic vein endothelial cells. The ED50 for this effect is ＜10 ng/mL. |
| Accession | P15692 |
| Alternative Names | Vascular Endothelial Growth Factor Isoform 121; VEGF121 |
| Species | Human |
| Expression System | CHO |
| Mol. Weight | 14.1kDa |
| Expression Region | Ala27-Arg147 |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | PBS, 5% Mannitol and 0.01% Tween 80, pH7.4. |
| Size | 10μg/50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Hematology
Supports hematopoietic niche vascularization indirectly.
Immunology
Modulates immune cell trafficking via vascular remodeling.
Stem Cell Research
Promotes endothelial differentiation and vascularization in organoids and stem cell cultures.
Cell Biology
Stimulates angiogenesis, endothelial proliferation, and survival.
Data Figures
Figure 1: Measured in a cell proliferation assay using HUVEC human umbilic vein endothelial cells. The ED50 for this effect is ＜10 ng/mL.
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
