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Sku: P100289-50 μl
Categories: Primary Antibodies

Specification

Full name AIF1 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene is induced by cytokines and interferon. Its protein product is thought to be involved in negative regulation of growth of vascular smooth muscle cells, which contributes to the anti-inflammatory response to vessel wall trauma. Three transcript variants encoding different isoforms have been found for this gene. Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
Swissprot No P55008
Gene Accession BC009474
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or AIF1 antigen-treated (Neutralization experiment) using P100289(AIF1 Antibody) at dilution 1/40
WB Positive control P100289-WB-1-P
WB Recommended dilution 17 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human breast cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P100289-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or AIF1 antigen-treated (Neutralization experiment) using P100289(AIF1 Antibody) at dilution 1/40

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