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Sku: P104481-50 μl

Specification

Full name AFP rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. [provided by RefSeq, Oct 2019] (The background information is obtained from official databases and does not represent the product information.)
Swissprot No P02771
Gene Accession BC027881
WB Predicted band size 69 kDa
WB Positive control
WB Recommended dilution 1000-5000
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human thyroid cancer
IHC Recommed dilution Recommended dilution: 30-150

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P104481-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or AFP antigen-treated (Neutralization experiment) using P104481(AFP Antibody) at dilution 1/25

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