Bcakground TGF-beta 2 (transforming growth factor beta 1) is one of three closely related mammalian members of the large TGF-beta superfamily that share a characteristic cystine knot structure . TGF-beta...
Bcakground FHepatocyte Growth Factor (HGF) also known as scatter factor and hepatopoietin A, is a pleiotropic protein in the plasminogen subfamily of S1 peptidases. It is a multidomain molecule that...
Bcakground Dickkopf related protein 1 (Dkk-1) is the founding member of the Dickkopf family of proteins that includes Dkk-1, -2, -3, -4, and a related protein, Soggy (1, 2). Dkk...
TRANCE (receptor activator of NF-kappa B ligand [RANK L], also called TNF-related activation-induced cytokine [TRANCE], osteoprotegrin ligand [OPGL], and osteoclast differentiation factor [ODF]), is a member of the tumor necrosis...
Bcakground CCL2 , also called monocyte chemotactic protein-1 (MCP-1) or JE, is a member of the C-C or beta chemokine family that is best known as a chemotactic agent for...
Bcakground Vascular Endothelial Growth Factor (VEGF) is a potent growth factor that promotes both angiogenesis and vascular permeability (1–3). It acts on endothelial cells by signaling primarily through two VEGF...
Bcakground Interleukin-33(IL-33) , also known as NF-HEV and DVS 27, is a 30 kDa proinflammatory protein that may also regulate gene transcription (1-3). DVS 27 was identifed as a gene...
Description Noggin, a secreted protein belonging to the TGF-β superfamily, functions as an endogenous antagonist of bone morphogenetic proteins (BMPs) and plays a key regulatory role in embryonic development, particularly...