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$336.00
Sku: Y01001-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by June 11, 2026
Description
FGF-9 (Fibroblast Growth Factor 9), a member of the FGF family, is a secreted protein that lacks a traditional signal peptide sequence and relies on a non-classical pathway for its secretion. It primarily activates downstream signaling pathways (such as MAPK and PI3K-AKT) by binding to FGFR1, FGFR2, and FGFR3 (IIIc isoform). FGF-9 is involved in neural development, angiogenesis, skeletal formation, and the progression of certain cancers (e.g., prostate cancer and glioma). This factor promotes cell proliferation and differentiation, enhances the proliferation of mesenchymal stem cells (MSCs), and maintains their multipotent differentiation potential. Additionally, FGF-9 participates in bone and cartilage regeneration and supports the survival and expansion of neural precursor cells. When combined with other growth factors, it can help maintain stemness and optimize culture systems for specific cell types.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y01001 |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | Measured in a cell proliferation assay using NIH3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 1-3 ng/mL. |
| Accession | P31371 |
| Alternative Names | Fibroblast Growth Factor 9; FGF-9; Glia-Activating Factor; GAF; Heparin-Binding Growth Factor 9; HBGF-9; FGF9 |
| Species | Human |
| Expression System | CHO |
| Mol. Weight | 23.2 kDa |
| Expression Region | Pro3-Ser208 |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | PBS, 5% Mannitol and 0.01% Tween 80, pH7.4. |
| Size | 10μg/50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Stem Cell Research
Supports proliferation and differentiation of neural stem cells, mesenchymal stem cells, and organoid development.
Cell Biology
Regulates cell proliferation, survival, tissue morphogenesis, and developmental signaling, especially in neural and musculoskeletal tissues.
Data Figures
Figure 1: Recombinant Human FGF9 (Cat. No. Y01001) SDS-PAGE (under reducing (R) & Non-reducing conditions. The gel was stained with Y01001 SDS-PAGE.
Figure 2: Recombinant Human FGF9 (Cat. No. Y01001) stimulates proliferation of NIH3T3 cells. The ED50 for this effect is 1-3 ng/mL. The bioactivity of Y01001 was higher than the other competing product.
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
