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Description
Chemical structure: macrolide
Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.
Specifications
| Shipping Conditions | RT |
| UNSPSC Code | 51101500 |
| UNSPSC Category | Antibiotics and Antimycotics |
| CAS | [114-07-8] |
| Grade | USP |
| DG | No |
| Storage | 18 to 25℃ |
| Sterile | Yes |
Application
Erythromycin has been used:
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as a supplement for nutrient broth medium for culturing green fluorescent protein (GFP)- expressing E. coli
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as a model drug to determine small intestinal (SMI) microtissue viability using the MTT assay{254
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as an antibiotic to study the treatment strategies of chronic infections
Biochem/physiol Actions
Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex.
Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.
Documents
Disclaimer: For laboratory research use only.
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