0 item(s)
View cart
You have no items in your shopping cart.
For research use only. We do not sell to patients.
$37.00
Sku: SML2519-5
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by July 21, 2026
Description
Anamorelin (RC-1291) is a non-peptidic ghrelin mimetic and orally active growth hormone secretagogue designed for research on ghrelin receptor signaling pathways. As a selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR, also known as GHS-R1a), Anamorelin is widely used to investigate receptor activation, growth hormone release mechanisms, appetite regulation, and metabolic signaling.
In laboratory studies, researchers often need reliable small molecules to evaluate how ghrelin-related pathways influence energy balance, body composition, and endocrine responses. Anamorelin provides a consistent research tool for studying GHSR-mediated biological processes, including GH/IGF-1 signaling and cancer cachexia-related metabolic changes.
With high chemical purity (≥98%), Anamorelin is suitable for biochemical assays, receptor signaling studies, pharmacological research, and laboratory research applications requiring a selective ghrelin receptor agonist.
For research use only. Not for human or veterinary therapeutic use.
Specification
| CAS No. | 249921-19-5 |
| Synonyms | RC-1291; ONO-7643; ST-1291 |
| Molecular Formula | C31H42N6O3 |
| Formula Weight | 546.70 |
| Purity | ≥98% |
| Formulation | Powder |
| Appearance | White to beige powder |
| Solubility | DMSO: 2 mg/mL, clear solution |
| Storage Temperature | −20°C |
| MDL Number | MFCD11973671 |
| InChI Key | VQPFSIRUEPQQPP-MXBOTTGLSA-N |
Features
- Selective GHSR Agonist: Activates ghrelin/growth hormone secretagogue receptor (GHSR) signaling pathways for endocrine and metabolic research.
- Orally Active Ghrelin Mimetic: A non-peptidic compound designed to mimic ghrelin receptor-mediated biological responses.
- Growth Hormone Secretagogue Activity: Suitable for studying GH release mechanisms and downstream GH/IGF-1 signaling pathways.
- Cancer Cachexia Research Tool: Used in research models investigating appetite regulation, body weight changes, and muscle metabolism.
- High Purity Research Compound: ≥98% purity supports reproducible biochemical and cell-based assay performance.
- Flexible Experimental Applications: Compatible with receptor studies, metabolic research, and pharmacological evaluation workflows.
Applications
- Ghrelin Receptor (GHSR) Signaling Research: Anamorelin is used as a selective GHSR agonist to investigate ghrelin receptor activation, downstream GPCR signaling pathways, and receptor-mediated cellular responses.
- Growth Hormone Secretion Studies: Used for studying growth hormone secretagogue activity, GH release mechanisms, and related endocrine signaling pathways including GH/IGF-1 regulation.
- Cancer Cachexia and Metabolic Research: Applied in research models exploring cancer-associated weight loss, appetite regulation, lean body mass changes, and metabolic dysfunction.
- Appetite Regulation Research: Supports studies investigating central ghrelin pathways involved in feeding behavior, energy balance, and nutritional metabolism.
- GPCR Pharmacology and Drug Discovery: Useful for receptor activation assays, pharmacological screening, and evaluation of ghrelin pathway modulators.
- Laboratory Research Applications: Suitable for laboratory studies evaluating metabolic signaling, endocrine responses, and small molecule activity.
Mechanism of Action
Anamorelin functions as a selective agonist of the ghrelin receptor (GHSR/GHS-R1a), a G protein-coupled receptor involved in growth hormone regulation, appetite control, and energy homeostasis.
Activation of GHSR signaling can stimulate downstream endocrine responses associated with growth hormone secretion and the GH/IGF-1 signaling axis. This makes Anamorelin a valuable research compound for studying hormone regulation and metabolic pathways.
Because ghrelin signaling is closely associated with appetite and body composition regulation, Anamorelin is frequently investigated in cancer cachexia research and metabolic signaling studies.
Research Advantages
Reliable performance of ghrelin receptor agonists is important for reproducible signaling studies. Consistent compound quality and appropriate handling support reliable experimental workflows.
Biofargo Anamorelin is supplied as a high-purity research compound to support consistent experimental workflows, including:
-
Receptor activation assays
-
Cell-based signaling studies
-
Endocrine pathway investigations
-
Metabolic research models
-
Drug discovery screening platforms
FAQ
What is Anamorelin (RC-1291) used for in research?
Anamorelin (RC-1291) is primarily used as a research compound for studying ghrelin receptor (GHSR) activation, growth hormone secretion, appetite regulation, metabolic signaling, and cancer cachexia-related pathways.
How does Anamorelin work as a GHSR agonist?
Anamorelin acts as a selective agonist of the ghrelin receptor (GHSR/GHS-R1a). Activation of this receptor can trigger downstream signaling associated with growth hormone release, appetite regulation, and energy balance.
Is Anamorelin a ghrelin mimetic?
Yes. Anamorelin is classified as a non-peptidic ghrelin mimetic because it activates ghrelin receptor signaling while maintaining a small molecule structure.
What research areas use Anamorelin?
Common research applications include GHSR signaling studies, endocrine research, growth hormone pathway investigations, metabolic research, appetite regulation studies, and cancer cachexia research.
For laboratory research or industrial use only.
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
