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Description
B-Raf inhibitor 1 (Compound 13) is a type IIA Raf inhibitor which bind to the DFG-out conformation with ki of 1 nM,1 nM,and 0.3 nM for B-Raf(WT), B-Raf(V600E) and C-Raf, respectively.
For research use only. We do not sell to patients.
Specification
| Formal Name | N1-(4-chlorophenyl)-6-methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]-1,5-isoquinolinediamine, dihydrochloride |
| CAS Number | 1191385-19-9 |
| Molecular Formula | C26H19ClN8 • 2HCl |
| Formula Weight | 551.9 |
| Purity | ≥98% |
| Formulation | A crystalline solid |
| Solubility | DMF: 1mg/mL DMSO: 10mg/mL DMSO:PBS (pH 7.2) (1:2): 0.3mg/mL |
| λmax | 288, 364 nm |
| InChi Code | InChI=1S/C26H19ClN8.2ClH/c1-15-4-9-19-18(10-12-29-24(19)34-17-7-5-16(27)6-8-17)21(15)35-25-20(3-2-11-28-25)22-23-26(32-13-30-22)33-14-31-23;;/h2-14H,1H3,(H,28,35)(H,29,34)(H,30,31,32,33);2*1H |
| InChi Key | HRLQRNBAJCQMMG-UHFFFAOYSA-N |
| Storage | -20°C |
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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