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Sku: 26792-25
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Description

B-Raf inhibitor 1 (Compound 13) is a type IIA Raf inhibitor which bind to the DFG-out conformation with ki of 1 nM,1 nM,and 0.3 nM for B-Raf(WT), B-Raf(V600E) and C-Raf, respectively.

For research use only. We do not sell to patients.

 

Specification

Formal Name N1-(4-chlorophenyl)-6-methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]-1,5-isoquinolinediamine, dihydrochloride
CAS Number 1191385-19-9
Molecular Formula C26H19ClN8 • 2HCl
Formula Weight 551.9
Purity ≥98%
Formulation A crystalline solid
Solubility DMF: 1mg/mL
DMSO: 10mg/mL
DMSO:PBS (pH 7.2) (1:2): 0.3mg/mL
λmax 288, 364 nm
InChi Code InChI=1S/C26H19ClN8.2ClH/c1-15-4-9-19-18(10-12-29-24(19)34-17-7-5-16(27)6-8-17)21(15)35-25-20(3-2-11-28-25)22-23-26(32-13-30-22)33-14-31-23;;/h2-14H,1H3,(H,28,35)(H,29,34)(H,30,31,32,33);2*1H
InChi Key HRLQRNBAJCQMMG-UHFFFAOYSA-N
Storage -20°C

 

Disclaimer: For laboratory research use only.

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