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Description
Glacial Acetic Acid (Acetic Acid, reagent grade, CAS 64-19-7) is a high-purity ACS reagent grade ethanoic acid (CH3COOH, ≥99.7%) widely used as a fundamental solvent and building block in organic synthesis, analytical chemistry, and industrial research workflows. In many laboratory applications, inconsistent acidity control, impurity interference, or trace metal contamination can significantly affect reaction reproducibility and analytical accuracy. This product is engineered to meet ACS reagent specifications, ensuring stable performance in demanding research environments where high-purity glacial acetic acid is required.
As a fully miscible, colorless, corrosive, and flammable liquid, glacial acetic acid serves as a key laboratory solvent for esterification reactions, buffer systems, HPLC-related workflows, and pharmaceutical intermediate synthesis. Its ultra-low impurity profile supports sensitive applications in organic synthesis, polymer chemistry, and trace analysis where analytical grade acetic acid is essential for reproducible results.
Specification
| Grade | Reagent |
| Formula | CH3COOH |
| MW | 60.05 |
| CAS | 64-19-7 |
| Meets ACS Reagent Specification | |
| Assay (by GC, corrected for water) | ≥99.7% |
| Maximum Allowable | |
| Colur (APHA) | ≤10 |
| Dilution Test | Passed Test |
| Residue after evaporation | ≤0.001% |
| Acetic Anhydride [(CH3CO)2O] | ≤0.01% |
| Chloride | ≤1 ppm |
| Sulfate | ≤1 ppm |
| Heavy metals | ≤0.5 ppm |
| Iron | ≤1 ppm |
| Substances reducing dichromate | Passed Test |
| Substances reducing permanganate | Passed Test |
| Titrable base | ≤0.0004 meq/g |
| Storage | Room temperature |
Features
- ACS Reagent Grade Purity: ≥99.7% assay ensures reliable performance in analytical grade and laboratory reagent applications.
- Low Impurity Profile: Ultra-low chloride, sulfate, and heavy metal content for sensitive organic synthesis and HPLC workflows.
- High Solubility & Miscibility: Fully miscible with water, ethanol, and ether, supporting flexible solvent system design.
- Stable Physical Properties: Well-defined boiling point (117–118°C) and melting point (16.2°C) for controlled experimental handling.
- Consistent Batch Quality: Manufactured under strict reagent-grade quality control for reproducible research results.
Applications
- Organic Synthesis: Widely used as a solvent and reaction medium for esterification, acetylation, and catalytic reactions.
- Analytical Chemistry: Suitable for HPLC mobile phase preparation and laboratory analytical grade solvent systems.
- Polymer & Material Science: Key raw material for vinyl acetate monomer (VAM), polyvinyl acetate (PVAc), and polyester intermediates.
- Pharmaceutical Research: Used in synthesis of acetylsalicylic acid (aspirin), acetaminophen intermediates, and active pharmaceutical ingredients.
- Industrial Chemistry: Production of acetic anhydride, cellulose acetate, dyes, pigments, and coatings.
- Buffer & pH Control Systems: Used in buffer formulation and acidity adjustment in biochemical workflows.
Documents
Frequently Asked Questions
What is glacial acetic acid used for in laboratory research?
Glacial acetic acid (ACS reagent grade, CAS 64-19-7) is widely used as a solvent in organic synthesis, esterification reactions, HPLC sample preparation, and analytical chemistry workflows requiring high-purity ethanoic acid.
Is this acetic acid suitable for HPLC or analytical applications?
Yes. With ≥99.7% purity and ultra-low ionic impurities, this analytical grade acetic acid is suitable for HPLC mobile phase preparation and sensitive analytical workflows.
Why is it called “glacial” acetic acid?
It is called glacial because pure acetic acid solidifies into ice-like crystals at temperatures below 16.6°C.
What makes ACS reagent grade important?
ACS reagent grade ensures strict control of impurities such as chloride, sulfate, and heavy metals, which is critical for reproducible laboratory and analytical results.
How should glacial acetic acid be stored safely?
Store at room temperature in a tightly sealed container, away from oxidizing agents and ignition sources due to its flammable and corrosive nature.
For laboratory research or industrial use only.
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.

