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Specification
| Full name | Fyn rabbit monoclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit monoclonal |
| Applications | WB |
| Host | Rabbit |
| Clone type | rabbit monoclonal |
| Target Background | Enables several functions, including cytoskeletal protein binding activity; protein tyrosine kinase activity; and transmembrane transporter binding activity. Involved in several processes, including negative regulation of dendritic spine maintenance; positive regulation of protein targeting to membrane; and positive regulation of tyrosine phosphorylation of STAT protein. Acts upstream of or within several processes, including cellular response to growth factor stimulus; nervous system development; and protein phosphorylation. Located in several cellular components, including Schaffer collateral - CA1 synapse; actin filament; and postsynaptic density. Is expressed in several structures, including alimentary system; central nervous system; cranial nerve; genitourinary system; and sensory organ. Used to study skin disease and skin squamous cell carcinoma. Human ortholog(s) of this gene implicated in Alzheimer's disease and schizophrenia. Orthologous to human FYN (FYN proto-oncogene, Src family tyrosine kinase). [provided by Alliance of Genome Resources, Apr 2022] |
| Swissprot No | P39688 |
| Gene Accession | 14360 |
| WB Predicted band size | 61 kDa |
| WB Positive control | |
| WB Recommended dilution | 500-2000 |
| IHC predicted cell location | nan |
| IHC positive control | nan |
| IHC Recommed dilution | nan |
Storage
-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.
WB PIC Description
P291712-WB-1-P
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