Trem-like transcript 2 protein (TLT-2; also TREML2) is a 33 kDa (unglycosylated) type I transmembrane cell surface receptor and member of the Trem family of receptor proteins. TLT-2 plays a...
TROP-2 is a cell surface glycoprotein highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors. The human TROP-2 protein is composed of...
Human TROP-2, also called tumor associated calcium signal transducer 2 (TACSTD2), GA733-1, gp50 and T16, is a type I cell surface glycoprotein that is highly expressed on human carcinomas. The...
Bcakground Vascular Endothelial Growth Factor (VEGF) is a potent growth factor that promotes both angiogenesis and vascular permeability (1–3). It acts on endothelial cells by signaling primarily through two VEGF...
Adiponectin is expressed in adipose tissue exclusively. It encodes a protein with similarity to collagens X and VIII and complement factor C1q. The encoded protein circulates in the plasma and...
The mouse AGT is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by...
Bcakground CCL2 , also called monocyte chemotactic protein-1 (MCP-1) or JE, is a member of the C-C or beta chemokine family that is best known as a chemotactic agent for...
The dickkopf family of proteins are secreted proteins characterized by two cysteine-rich domains that mediate protein-protein interactions. The encoded protein binds to the LRP6 co-receptor and inhibits beta-catenin-dependent Wnt signaling....