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Membrane component chromosome 1 surface marker 1; membrane component, chromosome 1, surface marker 1; Pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733; T16; TACSTD2; TROP2; TROP-2; TROP2GA7331; tumor-associated calcium signal transducer 2
$250.00
Sku: RP454-10UG
TROP-2 is a cell surface glycoprotein highly expressed on human carcinomas. It was originally identified as an antigen present on human gastrointestinal tumors. The human TROP-2 protein is composed of a putative 26 amino acid (aa) signal sequence, a 248 aa extracellular domain, a 23 aa transmembrane region and a 26 aa cytoplasmic domain. It is able to transduce an intracellular calcium signal with adhesive functions and probably plays a role in tumor growth (1-5).
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