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$350.00
Sku: TL-782-0050
Availability:
QUICK SHIP
In stock & estimated to ship in 1-2 days by March 15, 2026
Description
Fibroblast growth factor 4 (FGF4) is a member of the FGF family, playing crucial roles in embryonic development, cell proliferation, and differentiation. It promotes the proliferation of neural stem cells and induces neuronal differentiation in the postnatal brain.
In the context of metabolic research, FGF4 has been implicated in liver homeostasis and glucose regulation. Studies indicate that the loss of hepatic FGF4 in animal models can exacerbate high-fat diet-induced steatosis and liver injury.
Furthermore, similar to FGF1, FGF4 exhibits blood glucose-lowering effects. Long-term treatment with recombinant FGF4 (rFGF4) has been shown to improve insulin resistance and inhibit adipose tissue macrophage infiltration and inflammation.
This product is suitable for stem cell research, neurobiology, and metabolic disease-related studies in vitro.
Specifications
| Parameter | Specification |
|---|---|
| Expression Host | E. coli |
| Synonyms | HBGF-4; HST; HST-1; HSTF1; K-FGF; KFGF |
| Protein Sequence | DNA sequence encoding human FGF4 (NP_001998.1 Ser54–Leu206) expressed in E. coli |
| Molecular Weight | Predicted molecular weight is 16.92 kDa |
| Purity | >95%, analyzed by SDS-PAGE and HPLC |
| Endotoxin | <0.1 EU/μg |
| Purification Method | Chromatographic purification |
| Appearance | White lyophilized powder |
| Activity | Refer to COA for details |
Features
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E. coli–Expressed Human FGF4 (Ser54–Leu206)
Recombinant human FGF4 corresponding to Ser54–Leu206, expressed in E. coli with a predicted molecular weight of 16.92 kDa.
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High Purity Chromatographic Preparation
Purity >95% verified by SDS-PAGE and HPLC following chromatographic purification.
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Low Endotoxin Profile
Endotoxin level <0.01 EU/μg supporting sensitive in vitro cell culture applications.
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Defined Lyophilized Protein Format
Supplied as a white lyophilized powder with verified identity and consistent electrophoretic characteristics.
Applications
Neural Stem Cell Proliferation Research
Promotes proliferation of neural stem cells and supports neuronal differentiation studies.
Stem Cell Culture Studies
Applied in stem cell culture systems including MSC and iPSC-related research.
Metabolic Disease Models
Used in studies investigating liver homeostasis, glucose regulation, and insulin resistance mechanisms.
Cell Proliferation & Differentiation Studies
Supports research on cellular proliferation and differentiation pathways associated with the FGF signaling family.
MSC, iPSCs
Instructions
Reconstitute with sterile water. The recommended concentration is greater than 100 μg/mL. It is recommended to reconstitute at a concentration of 250 μg/mL. Please aliquot the protein to avoid repeated freezing and thawing.
Precautions
This product is only suitable for in vitro cell culture and cannot be used directly in clinical treatment.
Storage
-20℃
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
