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Pexidartinib (PLX3397) Purity 99.5%
Description Pexidartinib (PLX-3397) is a potent, orally active, and ATP-competitive inhibitor of colony stimulating factor 1 receptor (CSF1R/M-CSFR) and c-Kit, with IC₅₀ values of 20 nM and 10 nM, respectively....
$26.00
PI-3065
Description PI 3065 is a potent and selective PI 3-kinase p110δ inhibitor (IC50 = 5 nM; Ki = 1.5 nM). Exhibits >100-fold selectivity over p100α, p100γ and p100β isoforms (IC50...
$47.00
PLX-5622
Description PLX-5622 is a highly selective brain-penetrant CSF1R inhibitor (IC50=0.016 µM; Ki=5.9 nM) allowing for extended and specific microglial elimination, preceding and during pathology development. Key Features CSF1R Inhibition: PLX-5622...
$52.00
RMC-0331
Description RMC-0331 is a potent, selective and orally bioavailable SOS1 inhibitor. RMC-0331 is an in vivo tool compound that blocks RAS activation via disruption of the RAS-SOS1 interaction. Specification Catalog...
$402.00
RMC-6236 (Daraxonrasib)
Description RMC-6236, also known by its chemical synonym daraxonrasib, is a high-purity, first-in-class pan-RAS inhibitor designed exclusively as a research compound. Registered under CAS 2765081-21-6, this potent molecule targets the...
$1,339.00
RMC-7977
Description RMC-7977 is a reversible, tri-complex RAS inhibitor with broad spectrum activity for both mutant and wild-type (WT) KRAS, NRAS, and HRAS variants (a RASMULTI(ON) inhibitor). Preclinically, RMC-7977 demonstrated potent...
$412.00
Sebacic acid
Description General description Sebacic acid is a castor oil-derived dicarboxylic acid. It is widely used to produce polymers, plasticizers, lubricants, and corrosion retardants. It can act as a pH corrector in...
$59.00
SGX-523
Description A cell-permeable triazolopyridazine compound that acts as a potent, ATP-competitive (Ki = 2.7 & 23 nM using non-phosphorylated and phosphorylated MET kinase domain, respectively), and highly selective inhibitor against...
$26.00
