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Sku: P102905-50 μl

Specification

Full name TNFRSF13C rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.
Swissprot No Q96RJ3
Gene Accession NP_443177
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using P102905(TNFRSF13C Antibody) at dilution 1/45
WB Positive control P102905-WB-1-P
WB Recommended dilution 19 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human liver cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P102905-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue using P102905(TNFRSF13C Antibody) at dilution 1/45

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