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Sku: P291446-50 μl

Specification

Full name SNTA1 rabbit monoclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit monoclonal
Applications WB, IHC, IF
Host Rabbit
Clone type rabbit monoclonal
Target Background Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013]
Swissprot No Q13424
Gene Accession 6640
WB Predicted band size
WB Positive control P291446-WB-1-P
WB Recommended dilution 54 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: mouse colon
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

WB PIC Description

P291446-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded mouse colon tissue using P291446(SNTA1 Antibody) at dilution 1/50

When can I expect my order to ship?

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