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Specification
| Full name | RCOR1 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation. |
| Swissprot No | Q9UKL0 |
| Gene Accession | NP_055971 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue or RCOR1 antigen-treated (Neutralization experiment) using P107527(RCOR1 Antibody) at dilution 1/20 |
| WB Positive control | P107527-WB-1-P |
| WB Recommended dilution | 53 kDa |
| IHC predicted cell location | Predicted cell location: Nucleus |
| IHC positive control | Positive control: Human ovarian cancer |
| IHC Recommed dilution | Recommended dilution: 20-100 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P107527-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue or RCOR1 antigen-treated (Neutralization experiment) using P107527(RCOR1 Antibody) at dilution 1/20
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
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