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Sku: P108125-50 μl

Specification

Full name PTPN11 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia.
Swissprot No Q06124
Gene Accession BC008692
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or PTPN11 antigen-treated (Neutralization experiment) using P108125(PTPN11 Antibody) at dilution 1/60
WB Positive control P108125-WB-1-P
WB Recommended dilution 68 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human esophagus cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P108125-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or PTPN11 antigen-treated (Neutralization experiment) using P108125(PTPN11 Antibody) at dilution 1/60

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