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Full name | PTPN11 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. |
Swissprot No | Q06124 |
Gene Accession | BC008692 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human colorectal cancer tissue or PTPN11 antigen-treated (Neutralization experiment) using P108125(PTPN11 Antibody) at dilution 1/60 |
WB Positive control | P108125-WB-1-P |
WB Recommended dilution | 68 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human esophagus cancer |
IHC Recommed dilution | Recommended dilution: 50-200 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P108125-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or PTPN11 antigen-treated (Neutralization experiment) using P108125(PTPN11 Antibody) at dilution 1/60
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