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Full name | POLR2A rabbit monoclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit monoclonal |
Applications | WB, IHC, IF |
Host | Rabbit |
Clone type | rabbit monoclonal |
Target Background | This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA. [provided by RefSeq, Jul 2008] |
Swissprot No | P24928 |
Gene Accession | 5430 |
WB Predicted band size | |
WB Positive control | P291179-WB-1-P |
WB Recommended dilution | 217 kDa |
IHC predicted cell location | Predicted cell location: Nucleus |
IHC positive control | Positive control: Human breast cancer |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.
P291179-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using P291179(POLR2A Antibody) at dilution 1/50
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