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Sku: P291172-50 μl

Specification

Full name PML (phospho-Ser518) rabbit monoclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit monoclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit monoclonal
Target Background The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Swissprot No P29590
Gene Accession 5371
WB Predicted band size
WB Positive control P291172-WB-1-P
WB Recommended dilution 98 kDa
IHC predicted cell location Predicted cell location: Nucleus
IHC positive control Positive control: Human breast cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.

WB PIC Description

P291172-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using P291172(PML (phospho-Ser518) Antibody) at dilution 1/50

When can I expect my order to ship?

Most orders are filled and shipped within 2-3 business days from the time they are received.

Our standard shipping usually take 2-5 days.

We also provide express shippping for time-sensitive deliveries. 

Email contact@biofargo.com if you have any requirements.

 

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