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Sku: P105286-50 μl

Specification

Full name PGRMC2 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.
Swissprot No O15173
Gene Accession BC016692
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or PGRMC2 antigen-treated (Neutralization experiment) using P105286(PGRMC2 Antibody) at dilution 1/70
WB Positive control P105286-WB-1-P
WB Recommended dilution 24 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human thyroid cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P105286-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or PGRMC2 antigen-treated (Neutralization experiment) using P105286(PGRMC2 Antibody) at dilution 1/70

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