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Specification
| Full name | PARP1 (cleaved) rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
| Swissprot No | P09874 |
| Gene Accession | NP_001609 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or PARP1(cleaved) antigen-treated (Neutralization experiment) using P102456(PARP1(cleaved) Antibody) at dilution 1/25 |
| WB Positive control | P102456-WB-1-P |
| WB Recommended dilution | 113 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm, Nucleus |
| IHC positive control | Positive control: Human cervical cancer |
| IHC Recommed dilution | Recommended dilution: 25-100 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P102456-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue or PARP1(cleaved) antigen-treated (Neutralization experiment) using P102456(PARP1(cleaved) Antibody) at dilution 1/25
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