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Specification
| Full name | NDUFA1 rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. |
| Swissprot No | O15239 |
| Gene Accession | BC000266 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or NDUFA1 antigen-treated (Neutralization experiment) using P101016(NDUFA1 Antibody) at dilution 1/100 |
| WB Positive control | P101016-WB-1-P |
| WB Recommended dilution | 8 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human breast cancer |
| IHC Recommed dilution | Recommended dilution: 100-300 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P101016-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or NDUFA1 antigen-treated (Neutralization experiment) using P101016(NDUFA1 Antibody) at dilution 1/100
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