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Full name | MCM3 rabbit monoclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit monoclonal |
Applications | WB, IHC, IF |
Host | Rabbit |
Clone type | rabbit monoclonal |
Target Background | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2018] |
Swissprot No | P25205 |
Gene Accession | 4172 |
WB Predicted band size | |
WB Positive control | P290914-WB-1-P |
WB Recommended dilution | 91 kDa |
IHC predicted cell location | Predicted cell location: Nucleus |
IHC positive control | Positive control: Human tonsil |
IHC Recommed dilution | Recommended dilution: 50-100 |
-20°C, 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA. Avoid repeated freeze-thaw cycles.
P290914-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue using P290914(MCM3 Antibody) at dilution 1/50
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