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Sku: P107984-50 μl

Specification

Full name IL18 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background The protein encoded by this gene is a proinflammatory cytokine of the IL-1 family that is constitutively found as a precursor within the cytoplasm of a variety of cells including macrophages and keratinocytes. The inactive IL-18 precursor is processed to its active form by caspase-1, and is capable of stimulating interferon gamma production, and of regulating both T helper (Th) 1 and Th2 responses. This cytokine has been implicated in the injury of different organs, and in potentially fatal conditions characterized by a cytokine storm. In humans, IL-18 gene is located on chromosome 11. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Swissprot No Q14116
Gene Accession BC007007
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or IL18 antigen-treated (Neutralization experiment) using P107984(IL18 Antibody) at dilution 1/40
WB Positive control P107984-WB-1-P
WB Recommended dilution 22 kDa
IHC predicted cell location Predicted cell location: Secreted
IHC positive control Positive control: Human breast cancer
IHC Recommed dilution Recommended dilution: 50-100

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P107984-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue or IL18 antigen-treated (Neutralization experiment) using P107984(IL18 Antibody) at dilution 1/40

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