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Specification
| Full name | IL15RA rabbit polyclonal antibody |
| Alternative names | 50 μl/100 μl |
| Reactivity | rabbit polyclonal |
| Applications | WB, IHC |
| Host | Rabbit |
| Clone type | rabbit polyclonal |
| Target Background | This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. |
| Swissprot No | Q13261 |
| Gene Accession | NP_001230468 |
| WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue or IL15RA antigen-treated (Neutralization experiment) using P109746(IL15RA Antibody) at dilution 1/50 |
| WB Positive control | P109746-WB-1-P |
| WB Recommended dilution | 28 kDa |
| IHC predicted cell location | Predicted cell location: Cytoplasm |
| IHC positive control | Positive control: Human tonsil |
| IHC Recommed dilution | Recommended dilution: 50-200 |
Storage
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
WB PIC Description
P109746-WB-1-P
IHC PIC Description
Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or IL15RA antigen-treated (Neutralization experiment) using P109746(IL15RA Antibody) at dilution 1/50
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We also provide express shippping for time-sensitive deliveries.
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