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Sku: P102986-50 μl

Specification

Full name HIF1AN rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Factor inhibiting HIF-1 (FIH-1) exists as a homodimer and binds to HIF-1alpha. Specifically, FIH-1 operates as an asparaginyl hydroxylase. It catalyzes the hydroxylation of the beta-carbon of Asparagine residue 803 within the carboxy terminal transactivation domain of HIF-1alpha. This hydroxylation event blocks the association of HIF-1alpha with co-activators. FIH-1 also binds to von Hippel-Lindau (VHL) tumor suppressor protein, which represses transcriptional ac-tivity of HIF-1alpha. In transiently transfected human osteosarcoma cells, FIH-1 localizes to the cytoplasm. 
Swissprot No Q9NWT6
Gene Accession NP_060372
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human brain tissue or HIF1AN antigen-treated (Neutralization experiment) using P102986(HIF1AN Antibody) at dilution 1/40
WB Positive control P102986-WB-1-P
WB Recommended dilution 40 kDa
IHC predicted cell location Predicted cell location: Cytoplasm and Nucleus
IHC positive control Positive control: Human esophagus cancer
IHC Recommed dilution Recommended dilution: 50-300

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P102986-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or HIF1AN antigen-treated (Neutralization experiment) using P102986(HIF1AN Antibody) at dilution 1/40

When can I expect my order to ship?

Most orders are filled and shipped within 2-3 business days from the time they are received.

Our standard shipping usually take 2-5 days.

We also provide express shippping for time-sensitive deliveries. 

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