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Sku: P108336-50 μl

Specification

Full name FLT3 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia.
Swissprot No P36888
Gene Accession BC126350
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or FLT3 antigen-treated (Neutralization experiment) using P108336(FLT3 Antibody) at dilution 1/70
WB Positive control P108336-WB-1-P
WB Recommended dilution 113 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human liver cancer
IHC Recommed dilution Recommended dilution: 100-300

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P108336-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or FLT3 antigen-treated (Neutralization experiment) using P108336(FLT3 Antibody) at dilution 1/70

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