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Full name | FLT3 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. |
Swissprot No | P36888 |
Gene Accession | BC126350 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human prostate cancer tissue or FLT3 antigen-treated (Neutralization experiment) using P108336(FLT3 Antibody) at dilution 1/70 |
WB Positive control | P108336-WB-1-P |
WB Recommended dilution | 113 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human liver cancer |
IHC Recommed dilution | Recommended dilution: 100-300 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P108336-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue or FLT3 antigen-treated (Neutralization experiment) using P108336(FLT3 Antibody) at dilution 1/70
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