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Sku: P100643-50 μl

Specification

Full name ACTN4 rabbit polyclonal antibody
Alternative names 50 μl/100 μl
Reactivity rabbit polyclonal
Applications WB, IHC
Host Rabbit
Clone type rabbit polyclonal
Target Background Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes.
Swissprot No O43707
Gene Accession BC005033
WB Predicted band size Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or ACTN4 antigen-treated (Neutralization experiment) using P100643(ACTN4 Antibody) at dilution 1/60
WB Positive control P100643-WB-1-P
WB Recommended dilution 105 kDa
IHC predicted cell location Predicted cell location: Cytoplasm
IHC positive control Positive control: Human esophagus cancer
IHC Recommed dilution Recommended dilution: 50-200

Storage

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

WB PIC Description

P100643-WB-1-P

IHC PIC Description

Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue or ACTN4 antigen-treated (Neutralization experiment) using P100643(ACTN4 Antibody) at dilution 1/60

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