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Full name | SPTA1 rabbit polyclonal antibody |
Alternative names | 50 μl/100 μl |
Reactivity | rabbit polyclonal |
Applications | WB, IHC |
Host | Rabbit |
Clone type | rabbit polyclonal |
Target Background | Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is a tetramer made up of alpha-beta dimers linked in a head-to-head arrangement. This gene is one member of a family of alpha-spectrin genes. The encoded protein is primarily composed of 22 spectrin repeats which are involved in dimer formation. It forms weaker tetramer interactions than non-erythrocytic alpha spectrin, which may increase the plasma membrane elasticity and deformability of red blood cells. Mutations in this gene result in a variety of hereditary red blood cell disorders, including elliptocytosis type 2, pyropoikilocytosis, and spherocytic hemolytic anemia. |
Swissprot No | P02549 |
Gene Accession | NP_003117 |
WB Predicted band size | Immunohistochemical analysis of paraffin-embedded Human tonsil tissue or SPTA1 antigen-treated (Neutralization experiment) using P107372(SPTA1 Antibody) at dilution 1/25 |
WB Positive control | P107372-WB-1-P |
WB Recommended dilution | 280 kDa |
IHC predicted cell location | Predicted cell location: Cytoplasm |
IHC positive control | Positive control: Human thyroid cancer |
IHC Recommed dilution | Recommended dilution: 25-100 |
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
P107372-WB-1-P
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue or SPTA1 antigen-treated (Neutralization experiment) using P107372(SPTA1 Antibody) at dilution 1/25
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