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$172.00
Sku: Y06301-50ug
Availability:
AVAILABLE
In stock & estimated to ship in 3-7 days by March 18, 2026
Description
IFN-α2b (Interferon-α2b) is a cytokine produced by immune cells and belongs to the type I interferon family. It exerts antiviral, antiproliferative, and immunomodulatory effects primarily through activation of the JAK-STAT signaling pathway, and is widely used in the treatment of viral infections and tumors. Its antiviral activity is mediated by inducing the production of antiviral proteins that inhibit viral replication, making it useful for preventing or controlling viral contamination in cell culture. The antiproliferative function involves regulation of the cell cycle—such as arrest in the G1 phase—thereby inhibiting the growth of certain tumor cells or rapidly proliferating cell types, which supports research on cell cycle mechanisms and cancer therapy. Additionally, IFN-α2b enhances the expression of MHC class I molecules, promotes antigen presentation, and activates immune effector cells including NK cells and T cells, rendering it applicable in immunology-related studies.
Specifications
| Product Details | |
|---|---|
| Cat. No. | Y06301 |
| Purity | ≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining). |
| Endotoxin | ≤10 EU/mg by the LAL method. |
| Bioactivity | Measured in a VSV inhibition assay with wish cells. The ED50 this effect is ≤100 pg/mL, corresponding to a specific bioactivity is ≥2 ×108 units/mg. |
| Accession | P01563 |
| Alternative Names | Interferon Alpha-2; IFN-Alpha-2; Interferon Alpha-A; LeIF A; IFNA2 |
| Species | Human |
| Expression System | CHO |
| Mol. Weight | 19.2 kDa |
| Expression Region | Cys24-Glu188 |
| Tag Info | Tag free |
| Formulation | Lyophilized |
| Buffer | PBS, 5% Mannitol and 0.01% Tween 80, pH7.4. |
| Size | 10μg/50μg/1mg |
| Lead Time | Products are in stock, but custom products may require further consultation. |
| Reconstitution | It is recommended to redissolve in sterile deionized water. |
| Shipping | The product is shipped with blue ice. |
| Storage & Stability | 36 months at -20°C to -80°C in lyophilized state;6 months at -20°C to -80°C under sterile conditions after reconstitution;7-10 days at 2°C to 8°C under sterile conditions after reconstitution;Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
Features
- ✔ High Purity: This product undergoes stringent purification processes, achieving a purity level of over 95%,ensuring the reliability and reproducibility of experimental results.
- ✔ High Biological Activity: Verified through multiple activity assays, this product effectively induces the expectedbiological responses in target cells.
- ✔ Batch Consistency: Manufactured under strict production and quality control protocols to ensure highconsistency between batches.
- ✔ Animal-Free: Produced without the use of animal-derived components, meeting animal-free requirements.
Applications
Hematology
Modulates hematopoiesis, can induce HSC quiescence.
Immunology
Antiviral cytokine activating innate immune responses.
Stem Cell Research
Used in vitro to model antiviral responses in stem cells.
Cell Biology
Regulates antiviral pathways, proliferation, and survival signaling.
Data Figures
Figure 1: Recombinant Human IFN-α2b (Cat. No. Y06301) SDS-PAGE under reducing (R) & Non-reducing conditions. The gel was stained with Y06301 SDS-PAGE.
Figure 2: Measured in a VSV inhibition assay with Wish cells. The ED50 this effect is ≤100 pg/mL, corresponding to a specific bioactivity is ≥2 ×108 units/mg. The bioactivity of Y06301 was higher than the other competing product.
Instructions for Use
- Dissolve the lyophilized powder in an appropriate sterile buffer in a sterile environment before use.
- Prepare and dilute the solution according to experimental requirements to ensure accurate and reproducible results.
- Do not mix with other similar products to avoid cross-reactivity and potential interference.
Cautions
• Research Use Only: This product is not suitable for clinical diagnostics or therapeutic applications.
• Preservation: Handle according to instructions to preserve its activity and stability.
• Support: Contact our technical support team if you encounter any issues or questions.
Documents
When can I expect my order to ship?
Most orders are filled and shipped within 2-3 business days from the time they are received.
Our standard shipping usually take 2-5 days.
We also provide express shippping for time-sensitive deliveries.
Email contact@biofargo.com if you have any requirements.
